Sotabase

Career

· Ph.D. in Computational Biology, Cambridge University
· Senior Vice President of Strategic AI Partnerships, nference
· VP of Scientific Research, nference
· Investigator Scientist, Novartis Institutes for BioMedical Research (NIBR)
· Postdoctoral Researcher, Stanford University

Publications (100)

Molecular signatures of G-protein-coupled receptors
Nature · 2013
1,457
cited
Structural insights into μ-opioid receptor activation
Nature · 2015
799
cited
GPCR Dynamics: Structures in Motion.
Chemical Reviews · 2017
673
cited
Crystal Structure of an LSD-Bound Human Serotonin Receptor
Cell · 2017
388
cited
Comparison of two highly-effective mRNA vaccines for COVID-19 during periods of Alpha and Delta variant prevalence
medRxiv · 2021
262
cited
D4 dopamine receptor high-resolution structures enable the discovery of selective agonists
Science · 2017
216
cited
Mechanism of intracellular allosteric β2AR antagonist revealed by X-ray crystal structure
Nature · 2017
167
cited
FDA-authorized COVID-19 vaccines are effective per real-world evidence synthesized across a multi-state health system
medRxiv · 2021
141
cited
Diverse GPCRs exhibit conserved water networks for stabilization and activation
Proceedings of the National Academy of Sciences of the United States of America · 2019
137
cited
Structural and functional characterization of G protein–coupled receptors with deep mutational scanning
bioRxiv · 2019
120
cited
SARS-CoV-2 strategically mimics proteolytic activation of human ENaC
eLife · 2020
116
cited
Exploratory analysis of immunization records highlights decreased SARS-CoV-2 rates in individuals with recent non-COVID-19 vaccinations
Scientific Reports · 2020
113
cited
Augmented curation of clinical notes from a massive EHR system reveals symptoms of impending COVID-19 diagnosis
eLife · 2020
112
cited
Casirivimab–Imdevimab treatment is associated with reduced rates of hospitalization among high-risk patients with mild to moderate coronavirus disease-19
EClinicalMedicine · 2021
110
cited
Mechanism of Substrate Translocation in an Alternating Access Transporter
Cell · 2017
101
cited
Structured and disordered facets of the GPCR fold.
Current Opinion in Structural Biology · 2014
83
cited
Cryptic pocket formation underlies allosteric modulator selectivity at muscarinic GPCRs
Nature Communications · 2019
69
cited
Omicron variant of SARS-CoV-2 harbors a unique insertion mutation of putative viral or human genomic origin
2021
62
cited
Development of a multiomics model for identification of predictive biomarkers for COVID-19 severity: a retrospective cohort study
The Lancet Digital Health · 2022
58
cited
Knowledge synthesis from 100 million biomedical documents augments the deep expression profiling of coronavirus receptors
bioRxiv · 2020
57
cited
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