Sotabase

Career

· Assistant Professor, Bioengineering, UCLA Henry Samueli School of Engineering and Applied Science2025–
· Postdoctoral Researcher, Broad Institute of MIT and Harvard2021–2025
· Research Scientist, Massachusetts Institute of Technology2021–
· Postdoctoral Researcher, MIT Computational Biology Lab2021–2025
· Ph.D. in Biomedical Informatics, Stanford University2016–2021
· Technical Assistant, The University of Tokyo2016–2016
· B.S., Bioinformatics and Systems Biology, The University of Tokyo2012–2016
· Postdoctoral Researcher, MIT

Publications (63)

A cross-population atlas of genetic associations for 220 human phenotypes
Nature Genetics · 2021
1,649
cited
Mapping the human genetic architecture of COVID-19
Nature · 2021
804
cited
Genetics of 35 blood and urine biomarkers in the UK Biobank
Nature Genetics · 2020
622
cited
Human microglial state dynamics in Alzheimer’s disease progression
Cell · 2023
243
cited
Significant shared heritability underlies suicide attempt and clinically predicted probability of attempting suicide
bioRxiv · 2018
120
cited
Medical relevance of protein-truncating variants across 337,205 individuals in the UK Biobank study
bioRxiv · 2017
112
cited
A fast and scalable framework for large-scale and ultrahigh-dimensional sparse regression with application to the UK Biobank
bioRxiv · 2019
108
cited
WhichTF is functionally important in your open chromatin data?
PLoS Comput. Biol. · 2021
104
cited
Significant sparse polygenic risk scores across 813 traits in UK Biobank
PLoS Genetics · 2022
93
cited
Global Biobank Engine: enabling genotype-phenotype browsing for biobank summary statistics
bioRxiv · 2018
88
cited
A second update on mapping the human genetic architecture of COVID-19
Nature · 2022
75
cited
Components of genetic associations across 2,138 phenotypes in the UK Biobank highlight adipocyte biology
Nature Communications · 2019
70
cited
Single-cell dissection of the obesity-exercise axis in adipose-muscle tissues implies a critical role for mesenchymal stem cells
Cell Metabolism · 2022
70
cited
Assessing digital phenotyping to enhance genetic studies of human diseases
bioRxiv · 2019
50
cited
Rare protein-altering variants in ANGPTL7 lower intraocular pressure and protect against glaucoma
bioRxiv · 2019
44
cited
Sex-specific genetic effects across biomarkers
bioRxiv · 2019
39
cited
Fast Lasso method for Large-scale and Ultrahigh-dimensional Cox Model with applications to UK Biobank
bioRxiv · 2020
34
cited
Initial Review and Analysis of COVID-19 Host Genetics and Associated Phenotypes
2020
24
cited
A global atlas of genetic associations of 220 deep phenotypes
medRxiv · 2020
22
cited
Integration of rare expression outlier-associated variants improves polygenic risk prediction.
American Journal of Human Genetics · 2022
20
cited
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Yosuke Tanigawa | Researcher Profile | Sotabase | Sotabase