Sotabase

Career

· PhD, Biophysics, Stanford University2013–2019
· Assistant Professor, Columbia University Irving Medical Center
· Miller Postdoctoral Fellow, University of California, Berkeley
· BA, History, University of Pittsburgh
· BS, Molecular Biology, University of Pittsburgh

Publications (0)

GPCR Dynamics: Structures in Motion.
Chemical Reviews · 2017
672
cited
Structure of the μ Opioid Receptor-Gi Protein Complex
Nature · 2018
568
cited
Identification of Phosphorylation Codes for Arrestin Recruitment by G Protein-Coupled Receptors
Cell · 2017
383
cited
Structure of a Signaling Cannabinoid Receptor 1-G Protein Complex
Cell · 2019
363
cited
Structure of the M2 muscarinic receptor-β-arrestin complex in a lipid nanodisc
Nature · 2020
283
cited
Angiotensin Analogs with Divergent Bias Stabilize Distinct Receptor Conformations
Cell · 2019
237
cited
Molecular mechanism of biased signaling in a prototypical G protein–coupled receptor
Science · 2020
209
cited
Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR
Science · 2020
202
cited
Conformational transitions of a neurotensin receptor 1–Gi1 protein complex
Nature · 2019
194
cited
Catalytic activation of β-arrestin by GPCRs
Nature · 2018
173
cited
Molecular mechanism of GPCR-mediated arrestin activation
Nature · 2018
171
cited
Smoothened stimulation by membrane sterols drives Hedgehog pathway activity
Nature · 2019
170
cited
Mechanism of intracellular allosteric β2AR antagonist revealed by X-ray crystal structure
Nature · 2017
167
cited
Mu Opioid Receptor-Gi Protein Complex
2018
137
cited
Diverse GPCRs exhibit conserved water networks for stabilization and activation
Proceedings of the National Academy of Sciences of the United States of America · 2019
136
cited
How GPCR Phosphorylation Patterns Orchestrate Arrestin-Mediated Signaling
Cell · 2020
128
cited
Structural and functional characterization of G protein–coupled receptors with deep mutational scanning
bioRxiv · 2019
119
cited
Mechanism of Substrate Translocation in an Alternating Access Transporter
Cell · 2017
101
cited
Revealing Atomic-Level Mechanisms of Protein Allostery with Molecular Dynamics Simulations
PLoS Comput. Biol. · 2016
100
cited
Structure and mechanism of the cation–chloride cotransporter NKCC1
Nature · 2019
96
cited
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