Sotabase

Career

· Research Assistant, LAUNCH Lab2025–
· Product Studio Engineer, V1@Michigan2024–
· Intern, Facebook2021–
· Intern, Robinhood2021–
· Undergraduate Student, Carnegie Mellon University2020–
· Intern, Microsoft2020–

Publications (73)

PPARγ is a major driver of the accumulation and phenotype of adipose-tissue Treg cells
Nature · 2012
1,087
cited
Identification and isolation of candidate human keratinocyte stem cells based on cell surface phenotype.
Proceedings of the National Academy of Sciences of the United States of America · 1998
475
cited
Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions
Nature Biotechnology · 2017
454
cited
Directed evolution using dCas9-targeted somatic hypermutation in mammalian cells
Nature Methods · 2016
437
cited
Regulatory T Cells in Tumor-Associated Tertiary Lymphoid Structures Suppress Anti-tumor T Cell Responses.
Immunity · 2015
427
cited
NLR family member NLRC5 is a transcriptional regulator of MHC class I genes
Proceedings of the National Academy of Sciences of the United States of America · 2010
415
cited
The eEF2 Kinase Confers Resistance to Nutrient Deprivation by Blocking Translation Elongation
Cell · 2013
387
cited
Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens
Nature Communications · 2017
329
cited
CRISPR screens in cancer spheroids identify 3D growth specific vulnerabilities
Nature · 2020
244
cited
Location and phenotype of human adult keratinocyte stem cells of the skin.
Differentiation; research in biological diversity · 2004
237
cited
The impact of rare variation on gene expression across tissues
Nature · 2016
234
cited
A role for pericytes as microenvironmental regulators of human skin tissue regeneration.
Journal of Clinical Investigation · 2009
213
cited
Adhesive properties of human basal epidermal cells: an analysis of keratinocyte stem cells, transit amplifying cells, and postmitotic differentiating cells.
Journal of Investigative Dermatology · 2000
212
cited
CRISPR-Cas9 screens in human cells and primary neurons identify modifiers of C9orf72 dipeptide repeat protein toxicity
Nature Genetics · 2018
191
cited
Conventional type I dendric cells maintain a reservoir of proliferative tumor-antigen specific TCF-1+ CD8+ T cells in tumor-draining lymph nodes.
Immunity · 2021
173
cited
A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies
Nature Genetics · 2017
169
cited
Parallel shRNA and CRISPR-Cas9 screens enable antiviral drug target identification
Nature Chemical Biology · 2016
165
cited
Extensive tissue-regenerative capacity of neonatal human keratinocyte stem cells and their progeny.
Journal of Clinical Investigation · 2004
163
cited
Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens
Nature Genetics · 2018
149
cited
Establishment of 3D organotypic cultures using human neonatal epidermal cells
Nature Protocols · 2007
137
cited
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Amy Li | Researcher Profile | Sotabase | Sotabase