Sotabase

Career

· Research Intern, Microsoft Research New England2025–
· Mentor, Polymath Jr.2023–
· Algo Developer Intern, Hudson River Trading2022–
· Head Teaching Assistant for Math 0 (Intro to Proofs), Caltech2021–
· Ph.D. Candidate in Applied Mathematics, Harvard University2021–
· Counselor, PROMYS2021–
· JC (Junior Counselor), Canada/USA Mathcamp2018–
· B.S. in Mathematics, Caltech
· Volunteer, CHMMC (Caltech Harvey Mudd Math Competition)

Publications (60)

Humanity's Last Exam
Robotics · 2025
284
cited
Synthesis and SAR of 3,5-diamino-piperidine derivatives: novel antibacterial translation inhibitors as aminoglycoside mimetics.
Bioorganic & Medicinal Chemistry Letters · 2007
121
cited
Design of Development Candidate eFT226, a First in Class Inhibitor of Eukaryotic Initiation Factor 4A RNA Helicase.
Journal of Medicinal Chemistry · 2020
99
cited
Molecular recognition by glycoside pseudo base pairs and triples in an apramycin-RNA complex.
Angewandte Chemie · 2005
68
cited
Generative Social Choice
ACM Conference on Economics and Computation · 2023
56
cited
Anti-miRs Competitively Inhibit microRNAs in Argonaute Complexes
PLoS ONE · 2014
46
cited
Structure-Guided Discovery of Novel Aminoglycoside Mimetics as Antibacterial Translation Inhibitors
Antimicrobial Agents and Chemotherapy · 2005
45
cited
Targeting Oncogene mRNA Translation in B-Cell Malignancies with eFT226, a Potent and Selective Inhibitor of eIF4A
Molecular Cancer Therapeutics · 2020
36
cited
Algorithmic Collusion by Large Language Models
arXiv.org · 2024
29
cited
Zotatifin, an eIF4A-Selective Inhibitor, Blocks Tumor Growth in Receptor Tyrosine Kinase Driven Tumors
Frontiers in Oncology · 2021
27
cited
Preclinical Evaluation of eFT226, a Novel, Potent and Selective eIF4A Inhibitor with Anti-Tumor Activity in B-Cell Malignancies
2017
11
cited
Strategic Diastereoselective C1 Functionalization in the Aza-Rocaglamide Scaffold toward Natural Product-Inspired eIF4A Inhibitors.
Organic Letters · 2020
9
cited
Generative Social Choice: The Next Generation
International Conference on Machine Learning · 2025
8
cited
EconEvals: Benchmarks and Litmus Tests for LLM Agents in Unknown Environments
arXiv.org · 2025
7
cited
Generation and characterization of a tractable C. elegans model of tauopathy
GeroScience · 2021
6
cited
Discovery of Monovalent Direct Degraders of BRD4 that Act via the Recruitment of DCAF11
Molecular Cancer Therapeutics · 2024
5
cited
1-Aminomethyl SAR in a novel series of flavagline-inspired eIF4A inhibitors: Effects of amine substitution on cell potency and in vitro PK properties.
Bioorganic & Medicinal Chemistry Letters · 2021
4
cited
Abstract 2698: eFT226, a potent and selective inhibitor of eIF4A, is efficacious in preclinical models of lymphoma
Experimental and Molecular Therapeutics · 2019
4
cited
Discovery of novel small molecules that recruit DCAF11 for selective degradation of BRD4
European Journal of Cancer · 2022
3
cited
Abstract B133: eFT226, a first in class inhibitor of eIF4A1, targets FGFR1/2 and HER2 driven cancers
New Molecular Targets · 2019
2
cited
Sotabase