Sotabase

Career

· Professorial Fellow, Murray Edwards College (Current)1979–
· University Professor, University of Cambridge1979–

Publications (235)

Slowed conduction and ventricular tachycardia after targeted disruption of the cardiac sodium channel gene Scn5a
Proceedings of the National Academy of Sciences of the United States of America · 2002
412
cited
Modernized Classification of Cardiac Antiarrhythmic Drugs
Circulation · 2018
211
cited
Determinants of myocardial conduction velocity: implications for arrhythmogenesis
Frontiers in Physiology · 2013
183
cited
A new function for CD38/ADP-ribosyl cyclase in nuclear Ca2+ homeostasis
Nature Cell Biology · 1999
172
cited
Impaired Impulse Propagation in Scn5a-Knockout Mice: Combined Contribution of Excitability, Connexin Expression, and Tissue Architecture in Relation to Aging
Circulation · 2005
164
cited
Physiological studies of cortical spreading depression.
Biological Reviews of The Cambridge Philosophical Society · 2007
130
cited
Sinus node dysfunction following targeted disruption of the murine cardiac sodium channel gene Scn5a
Journal of Physiology · 2005
129
cited
Temperature dependence of human ether-a-go-go-related gene K+ currents.
American Journal of Physiology - Cell Physiology · 2006
122
cited
Cardiac Na+ Current Regulation by Pyridine Nucleotides
Circulation Research · 2009
119
cited
Effects of premature stimulation on HERG K+ channels
Journal of Physiology · 2001
114
cited
A new look at sodium channel β subunits
Open Biology · 2015
97
cited
Divalent cations mimic the inhibitory effect of extracellular ionised calcium on bone resorption by isolated rat osteoclasts: Further evidence for a “calcium receptor”
Journal of Cellular Physiology · 1991
91
cited
SCN5A and sinoatrial node pacemaker function.
Cardiovascular Research · 2007
89
cited
TGF-&bgr;1-Mediated Fibrosis and Ion Channel Remodeling Are Key Mechanisms in Producing the Sinus Node Dysfunction Associated With SCN5A Deficiency and Aging
Circulation: Arrhythmia and Electrophysiology · 2011
89
cited
Murine Electrophysiological Models of Cardiac Arrhythmogenesis.
Physiological Reviews · 2017
88
cited
Genetic Na+ channelopathies and sinus node dysfunction.
Progress in Biophysics and Molecular Biology · 2008
87
cited
A quantitative analysis of cell volume and resting potential determination and regulation in excitable cells
Journal of Physiology · 2004
85
cited
Atrial fibrillation and bisphosphonate therapy
Journal of Bone and Mineral Research · 2010
84
cited
Epac activation, altered calcium homeostasis and ventricular arrhythmogenesis in the murine heart
Pflügers Archiv: European Journal of Physiology · 2008
76
cited
Variable Nav1.5 Protein Expression from the Wild-Type Allele Correlates with the Penetrance of Cardiac Conduction Disease in the Scn5a +/− Mouse Model
PLoS ONE · 2010
75
cited
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Christopher Huang | Researcher Profile | Sotabase | Sotabase