Sotabase

Career

· Research Assistant, MIT Computer Science and Artificial Intelligence Laboratory (CSAIL)2024–
· Doctor of Philosophy - PhD, Massachusetts Institute of Technology2023–2021
· Research Assistant, MIT EECS2023–2024
· Research Fellow, The Rowland Institute at Harvard2022–2022
· Bachelor of Science - BSc, TU Delft2018–2021

Publications (110)

T-cell exhaustion in the tumor microenvironment
Cell Death and Disease · 2015
975
cited
Technology Roadmap for Flexible Sensors.
ACS Nano · 2023
927
cited
Local mutational diversity drives intratumoral immune heterogeneity in non-small cell lung cancer
Nature Communications · 2018
374
cited
Metabolic regulatory crosstalk between tumor microenvironment and tumor-associated macrophages
Theranostics · 2021
305
cited
Low-Dose Apatinib Optimizes Tumor Microenvironment and Potentiates Antitumor Effect of PD-1/PD-L1 Blockade in Lung Cancer
Cancer immunology research · 2019
257
cited
Type I interferon-mediated tumor immunity and its role in immunotherapy
Cellular and Molecular Life Sciences · 2022
232
cited
Heterogeneity of the tumor immune microenvironment and its clinical relevance
Experimental Hematology & Oncology · 2022
176
cited
Late-stage tumors induce anemia and immunosuppressive extramedullary erythroid progenitor cells
Nature Medicine · 2018
158
cited
EGFR-TKI down-regulates PD-L1 in EGFR mutant NSCLC through inhibiting NF-κB.
Biochemical and Biophysical Research Communications - BBRC · 2015
154
cited
Immune Landscape of Colorectal Cancer Tumor Microenvironment from Different Primary Tumor Location
Frontiers in Immunology · 2018
154
cited
Titin mutation associated with responsiveness to checkpoint blockades in solid tumors.
JCI Insight · 2019
134
cited
EZH2 Inhibitor GSK126 Suppresses Antitumor Immunity by Driving Production of Myeloid-Derived Suppressor Cells.
Cancer Research · 2019
133
cited
Targeting EZH2 histone methyltransferase activity alleviates experimental intestinal inflammation
Nature Communications · 2019
127
cited
Targeting miR-23a in CD8+ cytotoxic T lymphocytes prevents tumor-dependent immunosuppression.
Journal of Clinical Investigation · 2014
115
cited
Mechanism of Action of IL-7 and Its Potential Applications and Limitations in Cancer Immunotherapy
International Journal of Molecular Sciences · 2015
105
cited
High-throughput single-сell sequencing in cancer research
Signal Transduction and Targeted Therapy · 2022
104
cited
Resolution of Cancer-Promoting Inflammation: A New Approach for Anticancer Therapy
Frontiers in Immunology · 2017
103
cited
Tumor-induced erythroid precursor-differentiated myeloid cells mediate immunosuppression and curtail anti-PD-1/PD-L1 treatment efficacy.
Cancer Cell · 2022
95
cited
A Soft Resistive Acoustic Sensor Based on Suspended Standing Nanowire Membranes with Point Crack Design
Advanced Functional Materials · 2020
91
cited
CD133+ ovarian cancer stem-like cells promote non-stem cancer cell metastasis via CCL5 induced epithelial-mesenchymal transition
OncoTarget · 2015
86
cited
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