Sotabase

Career

· Teaching Faculty, University of Wisconsin-Madison2023–
· Course Instructor, University of Wisconsin-Madison2018–2023
· Doctor of Philosophy - PhD, Computer Science, 4.0/4.0, University of Wisconsin-Madison2018–2023
· Teaching Assistant, University of Wisconsin-Madison2018–2023
· Course Instructor, University of Toronto2015–2016
· Doctor of Philosophy (PhD), Economics, N/A, University of Toronto2012–2018
· Master of Arts (MA), Economics, 4.0/4.0, University of Toronto2011–2012
· Teaching Assitant, University of Toronto2011–2017
· B, Mathematical Finance, 91/100, University of Waterloo2007–2011

Publications (28)

Transcription generates positively and negatively supercoiled domains in the template
Cell · 1988
670
cited
Transcription-driven supercoiling of DNA: Direct biochemical evidence from in vitro studies
Cell · 1989
303
cited
Proliferation-dependent regulation of DNA topoisomerase II in cultured human cells.
Cancer Research · 1988
249
cited
A Promoter Relay Mechanism for Sequential Gene Activation
Journal of Bacteriology · 1998
56
cited
A Cis-spreading Nucleoprotein Filament Is Responsible for the Gene Silencing Activity Found in the Promoter Relay Mechanism*
Journal of Biological Chemistry · 2005
55
cited
Long-range interaction between two promoters: Activation of the leu-500 promoter by a distant upstream promoter
Cell · 1995
54
cited
LeuO Protein Delimits the Transcriptionally Active and Repressive Domains on the Bacterial Chromosome*
Journal of Biological Chemistry · 2005
49
cited
LeuO Expression in Response to Starvation for Branched-chain Amino Acids*
Journal of Biological Chemistry · 2001
48
cited
A 72-Base Pair AT-rich DNA Sequence Element Functions as a Bacterial Gene Silencer*
Journal of Biological Chemistry · 2001
32
cited
Transcription-driven DNA supercoiling and gene expression control.
Frontiers in Bioscience · 2003
31
cited
Suppression of leu-500 Mutation intopA + Salmonella typhimuriumStrains
Journal of Biological Chemistry · 1998
25
cited
DNA supercoiling and transcription control: a model from the study of suppression of the leu-500 mutation in Salmonella typhimurium topA- strains.
Progress in Nucleic Acid Research and Molecular Biology · 2003
23
cited
LeuO-mediated Transcriptional Derepression*
Journal of Biological Chemistry · 2003
23
cited
One-step purification of bacterially expressed recombinant transducin α-subunit and isotopically labeled PDE6 γ-subunit for NMR analysis
2007
18
cited
Agrobacterium-mediated transient MaFT expression in mulberry (Morus alba L.) leaves
Bioscience, biotechnology and biochemistry · 2015
13
cited
Crystal structure and biochemical studies of the bifunctional DNA primase-polymerase from phage NrS-1.
Biochemical and Biophysical Research Communications - BBRC · 2019
12
cited
Crystal structure of the Vibrio cholerae VqmA–ligand–DNA complex provides insight into ligand-binding mechanisms relevant for drug design
Journal of Biological Chemistry · 2019
12
cited
Crystal structure details of Vibrio fischeri DarR and mutant DarR-M202I from LTTR family reveals their activation mechanism.
International Journal of Biological Macromolecules · 2021
9
cited
Large conformation shifts of Vibrio cholerae VqmA dimer in the absence of target DNA provide insight into DNA-binding mechanisms of LuxR-type receptors.
Biochemical and Biophysical Research Communications - BBRC · 2019
8
cited
Crystal structures of phage NrS-1 N300-dNTPs-Mg2+ complex provide molecular mechanisms for substrate specificity.
Biochemical and Biophysical Research Communications - BBRC · 2019
7
cited
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