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Career

· CHTC Research System Administrator, University of Wisconsin-Madison Center for High Throughput Computing (CHTC)2022–

Publications (46)

Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant
Nature Genetics · 2005
755
cited
Protein tyrosine phosphatases and the immune response
Nature reviews. Immunology · 2005
365
cited
Activation of the Cooh-Terminal Src Kinase (Csk) by Camp-Dependent Protein Kinase Inhibits Signaling through the T Cell Receptor
Journal of Experimental Medicine · 2001
351
cited
Role of PTPN22 in type 1 diabetes and other autoimmune diseases.
Seminars in Immunology · 2006
351
cited
Molecular mechanisms for protein kinase A-mediated modulation of immune function.
Cellular Signalling · 2002
213
cited
Protein tyrosine phosphatases in autoimmunity.
Annual Review of Immunology · 2008
172
cited
Structure, function, and regulation of human cAMP-dependent protein kinases.
Advances in second messenger and phosphoprotein research · 1997
169
cited
Protein tyrosine phosphatase PTPN22 in human autoimmunity
Autoimmunity · 2007
168
cited
Release from Tonic Inhibition of T Cell Activation through Transient Displacement of C-terminal Src Kinase (Csk) from Lipid Rafts*
Journal of Biological Chemistry · 2001
164
cited
LYP inhibits T cell activation when dissociated from CSK
Nature Chemical Biology · 2012
148
cited
TCR- and CD28-Mediated Recruitment of Phosphodiesterase 4 to Lipid Rafts Potentiates TCR Signaling1
Journal of Immunology · 2004
146
cited
Inhibition of Antigen-Specific T Cell Proliferation and Cytokine Production by Protein Kinase A Type I1
Journal of Immunology · 2002
106
cited
Combined Spatial and Enzymatic Regulation of Csk by cAMP and Protein Kinase A Inhibits T Cell Receptor Signaling*
Journal of Biological Chemistry · 2003
86
cited
T Cell-Signaling Network Analysis Reveals Distinct Differences between CD28 and CD2 Costimulation Responses in Various Subsets and in the MAPK Pathway between Resting and Activated Regulatory T Cells
Journal of Immunology · 2011
67
cited
Multidentate small-molecule inhibitors of vaccinia H1-related (VHR) phosphatase decrease proliferation of cervix cancer cells.
Journal of Medicinal Chemistry · 2009
63
cited
Protein Kinase A Intersects Src Signaling in Membrane Microdomains*
Journal of Biological Chemistry · 2003
59
cited
The autoimmune-predisposing variant of lymphoid tyrosine phosphatase favors T helper 1 responses.
Human Immunology · 2013
52
cited
Knockdown of C‐terminal Src kinase by siRNA‐mediated RNA interference augments T cell receptor signaling in mature T cells
European Journal of Immunology · 2004
49
cited
Activation of C-terminal Src kinase (Csk) by phosphorylation at serine-364 depends on the Csk-Src homology 3 domain.
Biochemical Journal · 2003
48
cited
A Weak Lck Tail Bite Is Necessary for Lck Function in T Cell Antigen Receptor Signaling*
Journal of Biological Chemistry · 2007
35
cited
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