Sotabase

Career

· Contributing Author, SGLang2025–
· Climate And Artificial Intelligence Researcher, aramco2024–2024
· Doctoral Researcher, Stanford Doerr School of Sustainability2022–
· Seed A Investor, Angel Investor2021–
· ESG Data Analyst, MioTech2021–2021
· Energy Analyst, Environmental Defense Fund2019–2019
· Founding Partner, YSI - Young Sustainable Impact2017–2022
· Master of Science - MS Atmosphere/Energy Engineering, Stanford University

Publications (87)

Key Parameters of Tumor Epitope Immunogenicity Revealed Through a Consortium Approach Improve Neoantigen Prediction
Cell · 2020
416
cited
A variant by any name: quantifying annotation discordance across tools and clinical databases
Genome Medicine · 2016
68
cited
Are minor alleles more likely to be risk alleles?
BMC Medical Genomics · 2018
65
cited
High prevalence of focal and multi-focal somatic genetic variants in the human brain
Nature Communications · 2018
65
cited
Achieving high-sensitivity for clinical applications using augmented exome sequencing
Genome Medicine · 2015
59
cited
Early somatic mosaicism is a rare cause of long-QT syndrome
Proceedings of the National Academy of Sciences of the United States of America · 2016
48
cited
Prediction of Immunotherapy Response in Melanoma through Combined Modeling of Neoantigen Burden and Immune-Related Resistance Mechanisms
Clinical Cancer Research · 2021
41
cited
Precision Neoantigen Discovery Using Large-scale Immunopeptidomes and Composite Modeling of MHC Peptide Presentation
bioRxiv · 2021
37
cited
A machine learning algorithm with subclonal sensitivity reveals widespread pan-cancer human leukocyte antigen loss of heterozygosity
Nature Communications · 2022
22
cited
Precision neoantigen discovery using large-scale immunopeptidomes and composite modeling of MHC peptide presentation.
Molecular & Cellular Proteomics · 2023
8
cited
Genetic analysis in a patient with nine primary malignant neoplasms: a rare case of Li-Fraumeni syndrome.
Oncology Report · 2016
6
cited
692 Circulating tumor DNA analysis of advanced hepatocellular cancer (HCC) patients treated with neoantigen targeted personalized cancer DNA vaccine (GNOS-PV02) in combination with plasmid IL-12 (pIL12) and anti-PD1 (pembrolizumab)
Regular and Young Investigator Award Abstracts · 2022
5
cited
Abstract 1457: Genomic characterization of a PDX model of T-DM1-resistant HER2+ invasive ductal carcinoma using augmented exome sequencing
2015
3
cited
Analytic validation of NeXT Dx™, a comprehensive genomic profiling assay
OncoTarget · 2023
3
cited
Abstract 1989: Enhanced whole exome profiling of tumor circulating cell-free DNA enables sensitive assessment of tumor mutations
Clinical Trials · 2020
2
cited
Abstract 4536: Applying immunopeptidomics and machine learning to improve neoantigen prediction for therapeutic and diagnostic use
Cancer Chemistry · 2019
2
cited
Validation of an exome and transcriptome based diagnostic platform enabling clinical cancer therapy selection and emerging composite biomarkers for immunotherapy.
2020
2
cited
20 Tumor-informed liquid biopsy monitoring of evolving therapeutic resistance mechanisms in head and neck squamous cell carcinoma patients receiving anti-PD-1 therapy
Journal for ImmunoTherapy of Cancer · 2021
1
cited
Abstract 1334: A diagnostic platform for precision cancer therapy enabling composite biomarkers by combining tumor and immune features from an enhanced exome and transcriptome
Molecular and Cellular Biology / Genetics · 2020
1
cited
Abstract 3616: Fix the fixation: effect of formalin fixation on targeted sequencing, variant calling and gene expression
2016
1
cited
Sotabase
Rich Chen | Researcher Profile | Sotabase | Sotabase