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Career

· Postdoctoral Researcher, UC Berkeley2024–
· PhD Student in EECS, UC Berkeley2020–2024
· Postdoctoral Researcher, UC Berkeley Automation Lab (AUTOLAB)2020–

Publications (33)

Biosynthetic capacity, metabolic variety and unusual biology in the CPR and DPANN radiations
Nature Reviews Microbiology · 2018
342
cited
Archaeal Elp3 catalyzes tRNA wobble uridine modification at C5 via a radical mechanism.
Nature Chemical Biology · 2014
108
cited
Chemical trapping and crystal structure of a catalytic tRNA guanine transglycosylase covalent intermediate
Nature Structural Biology · 2003
104
cited
Reconstituting Bacterial RNA Repair and Modification in Vitro
Science · 2009
63
cited
Biochemical and structural studies of A-to-I editing by tRNA:A34 deaminases at the wobble position of transfer RNA.
Biochemistry · 2005
51
cited
Conformational change of pseudouridine 55 synthase upon its association with RNA substrate.
Nucleic Acids Research · 2005
51
cited
Crystallographic snapshots of eukaryotic dimethylallyltransferase acting on tRNA: Insight into tRNA recognition and reaction mechanism
Proceedings of the National Academy of Sciences of the United States of America · 2008
51
cited
Molecular mechanisms of the CdnG-Cap5 antiphage defense system employing 3′,2′-cGAMP as the second messenger
Nature Communications · 2021
51
cited
Dissecting the roles of a strictly conserved tyrosine in substrate recognition and catalysis by pseudouridine 55 synthase.
Biochemistry · 2005
41
cited
Different thermodynamic binding mechanisms and peptide fine specificities associated with a panel of structurally similar high-affinity T cell receptors.
Biochemistry · 2008
36
cited
Structural and biochemical insights into 2′-O-methylation at the 3′-terminal nucleotide of RNA by Hen1
Proceedings of the National Academy of Sciences of the United States of America · 2009
35
cited
Double methylation of tRNA-U54 to 2′-O-methylthymidine (Tm) synergistically decreases immune response by Toll-like receptor 7
Nucleic Acids Research · 2018
27
cited
Unique 2'-O-methylation by Hen1 in eukaryotic RNA interference and bacterial RNA repair.
Biochemistry · 2012
26
cited
Crystal structure of QueC from Bacillus subtilis: An enzyme involved in preQ1 biosynthesis
Proteins: Structure, Function, and Bioinformatics · 2008
21
cited
Structural and mutational studies of the catalytic domain of colicin E5: a tRNA-specific ribonuclease.
Biochemistry · 2005
21
cited
Structure of tRNA dimethylallyltransferase: RNA modification through a channel.
Journal of Molecular Biology · 2008
20
cited
Molecular basis of bacterial protein Hen1 activating the ligase activity of bacterial protein Pnkp for RNA repair
Proceedings of the National Academy of Sciences of the United States of America · 2012
19
cited
Molecular basis of inhibition of the ribonuclease activity in colicin E5 by its cognate immunity protein.
Journal of Molecular Biology · 2006
15
cited
Reconstitution and substrate specificity for isopentenyl pyrophosphate of the antiviral radical SAM enzyme viperin
Journal of Biological Chemistry · 2018
13
cited
Enzymatic characterization and mutational studies of TruD--the fifth family of pseudouridine synthases.
Archives of Biochemistry and Biophysics · 2009
11
cited
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