Sotabase

Career

· Flintridge Foundation Professor of Political and Computational Social Science, California Institute of Technology2024–
· Associate Professor, California Institute of Technology1995–2002
· Assistant Professor, California Institute of Technology1992–1995
· Ph.D. in Political Science, Duke University1990–1992
· M.A. in Political Science, Duke University1986–1990
· Bachelor's degree, Carleton College

Publications (35)

Cloning and Expression of a 5‐Hydroxytryptamine7 Receptor Positively Coupled to Adenylyl Cyclase
Journal of Neurochemistry · 1994
185
cited
Activation and selective inhibition of a cyclic AMP-specific phosphodiesterase, PDE-4D3.
Molecular Pharmacology · 1995
128
cited
A separation method for the assay of adenylylcyclase, intracellular cyclic AMP, and cyclic-AMP phosphodiesterase using tritium-labeled substrates.
Analytical Biochemistry · 1992
85
cited
Inhibitors of cyclic AMP phosphodiesterase. 3. Synthesis and biological evaluation of pyrido and imidazolyl analogues of 1,2,3,5-tetrahydro-2-oxoimidazo[2,1-b]quinazoline.
Journal of Medicinal Chemistry · 1988
81
cited
The cDNA of a human lymphocyte cyclic-AMP phosphodiesterase (PDE IV) reveals a multigene family.
Gene · 1993
72
cited
Elevated intracellular cyclic AMP inhibits chemotaxis in human eosinophils.
Cellular Signalling · 1995
55
cited
Regulation of cyclic AMP metabolism in human platelets. Sequential activation of adenylate cyclase and cyclic AMP phosphodiesterase by prostaglandins.
Molecular Pharmacology · 1981
55
cited
The action of SDZ 205,557 at 5‐hydroxytryptamine (5‐HT3 and 5‐HT4) receptors
British Journal of Pharmacology · 1993
54
cited
Inhibitors of cyclic AMP phosphodiesterase. 1. Analogues of cilostamide and anagrelide.
Journal of Medicinal Chemistry · 1987
39
cited
A potent and selective inhibitor of cyclic AMP phosphodiesterase with potential cardiotonic and antithrombotic properties.
Molecular Pharmacology · 1986
36
cited
Inhibitors of cyclic AMP phosphodiesterase. 2. Structural variations of N-cyclohexyl-N-methyl-4-[(1,2,3,5-tetrahydro- 2-oxoimidazo[2,1-b]quinazolin-7-yl)-oxy]butyramide (RS-82856).
Journal of Medicinal Chemistry · 1987
36
cited
Inhibitors of cyclic AMP phosphodiesterase. 4. Synthesis and evaluation of potential prodrugs of lixazinone (N-cyclohexyl-N-methyl-4-[(1,2,3,5-tetrahydro-2- oxoimidazo[2,1-b]quinazolin-7-yl)-oxy]butyramide, RS-82856).
Journal of Medicinal Chemistry · 1988
18
cited
Stimulation of prostaglandin D2 receptors on human platelets by analogs of prostacyclin.
Prostaglandins · 1991
13
cited
The 5-hydroxytryptamine (5-HT)7 receptor
1994
9
cited
11 – An Isoform-selective Inhibitor of Cyclic AMP-Specific Phosphodiesterase (PDE4) with Anti-inflammatory Properties
1996
8
cited
Cloned and Native Guinea Pig 5‐ht7 Receptors
Annals of the New York Academy of Sciences · 1997
6
cited
A semiautomated method for the assay of cyclic adenosine 5'-monophosphate phosphodiesterase.
Analytical Biochemistry · 1996
2
cited
RS-82856, a selective phosphodiesterase inhibitor with inotropic, afterload reduction and antithrombotic properties.
Proceedings of the Western Pharmacology Society · 1987
2
cited
Electrochemical evaluation of the interaction between ascorbic acid and the cardiotonic drug RS-82856.
Drug design and delivery · 1987
1
cited
Phosphate exchange between high-energy phosphate compounds in resting crustacean muscle.
Quarterly Journal of Experimental Physiology and Cognate Medical Sciences · 1980
1
cited
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