Sotabase

Career

· Co Director, Norlab2015–
· Full Professor, Laval University2010–
· PhD, Computer Science, McGill University2004–2009
· PhD Student, McGill University2004–2009
· Master, Computer Science, Northeastern University2000–2003
· Software Engineer, NMS Communications1999–2003
· System Specialist, CAE1996–1998
· Bachelor, Engineering Physics, Laval University1992–1996

Publications (136)

Structure-based discovery of opioid analgesics with reduced side effects
Nature · 2016
834
cited
PRESTO-TANGO: an open-source resource for interrogation of the druggable human GPCR-ome
Nature Structural &Molecular Biology · 2015
591
cited
Molecular control of δ-opioid receptor signalling
Nature · 2014
466
cited
A New DREADD Facilitates the Multiplexed Chemogenetic Interrogation of Behavior
Neuron · 2015
354
cited
The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy.
Immunity · 2012
288
cited
Regulators of G-Protein Signaling and Their Gα Substrates: Promises and Challenges in Their Use as Drug Discovery Targets
Pharmacological Reviews · 2011
243
cited
Structural basis for bifunctional peptide recognition at human δ-Opioid receptor
Nature Structural &Molecular Biology · 2015
173
cited
DREADDs: novel tools for drug discovery and development.
Drug Discovery Today · 2014
85
cited
Nm23-H2 Interacts with a G Protein-coupled Receptor to Regulate Its Endocytosis through an Rac1-dependent Mechanism*
Journal of Biological Chemistry · 2004
57
cited
The RGS protein inhibitor CCG-4986 is a covalent modifier of the RGS4 Galpha-interaction face.
Biochimica et Biophysica Acta · 2007
56
cited
Peroxiredoxin‐4 interacts with and regulates the thromboxane A2 receptor
FEBS Letters · 2007
46
cited
Oligomerization of the α and β isoforms of the thromboxane A2 receptor : Relevance to receptor signaling and endocytosis
2005
43
cited
Relative Ratios of Human Seasonal Coronavirus Antibodies Predict the Efficiency of Cross-Neutralization of SARS-CoV-2 Spike Binding to ACE2
medRxiv · 2021
43
cited
A Non-Canonical Function of Gβ as a Subunit of E3 Ligase in Targeting GRK2 Ubiquitylation.
Molecules and Cells · 2015
35
cited
Design and Discovery of Functionally Selective Serotonin 2C (5-HT2C) Receptor Agonists.
Journal of Medicinal Chemistry · 2016
35
cited
In Vitro and In Vivo Characterization of the Alkaloid Nuciferine
PLoS ONE · 2016
35
cited
Arsenal of nanobodies shows broad-spectrum neutralization against SARS-CoV-2 variants of concern in vitro and in vivo in hamster models
Communications Biology · 2022
33
cited
Optimization of 2-phenylcyclopropylmethylamines as selective serotonin 2C receptor agonists and their evaluation as potential antipsychotic agents.
Journal of Medicinal Chemistry · 2015
33
cited
G-protein signaling modulator-3, a gene linked to autoimmune diseases, regulates monocyte function and its deficiency protects from inflammatory arthritis.
Molecular Immunology · 2013
32
cited
High efficiency transient transfection of genes in human umbilical vein endothelial cells by electroporation.
JIM - Journal of Immunological Methods · 2001
31
cited
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