Michael Lee

Visiting Professor, Resilient Workforces Institute, Singapore Management University

52 h-index · 20.4K citations · 109 papers

My research interests are in the areas of robot intelligencehuman-robot interactionand adaptive control. I am particularly interested in developing robots that can learn and adapt to new environments and tasks. I am also interested in the use of machine learning techniques for robot control.

Labs

Robot Intelligence Lab · UCLA

Collaborators

Career

· Visiting Professor, Resilient Workforces Institute, Singapore Management University2025–

· Honorary Visiting Research Fellow, School Of Psychology, University of Adelaide2023–

· Professor Of Cognitive Sciences, UC Irvine2006–

· Associate Professor Psychology, University of Adelaide2001–2006

· Senior Research Scientist, Defence Science and Technology Organisation1997–2001

· Doctor of Philosophy (PhD), Cognitive Science, University of Adelaide1994–1997

· High school, Matriculation, Pembroke School1984–1987

Publications (109)

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

Neuron · 1995

1,517

cited

Familial Alzheimer's Disease–Linked Presenilin 1 Variants Elevate Aβ1–42/1–40 Ratio In Vitro and In Vivo

Neuron · 1996

1,470

cited

Mutant presenilins specifically elevate the levels of the 42 residue β-amyloid peptide in vivo: evidence for augmentation of a 42-specific γ secretase

2004

1,399

cited

ALS-Linked SOD1 Mutant G85R Mediates Damage to Astrocytes and Promotes Rapidly Progressive Disease with SOD1-Containing Inclusions

Neuron · 1997

1,361

cited

Endoproteolysis of Presenilin 1 and Accumulation of Processed Derivatives In Vivo

Neuron · 1996

1,069

cited

Accelerated Amyloid Deposition in the Brains of Transgenic Mice Coexpressing Mutant Presenilin 1 and Amyloid Precursor Proteins

Neuron · 1997

1,063

cited

Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase.

Human Molecular Genetics · 2004

790

cited

Altered Reactivity of Superoxide Dismutase in Familial Amyotrophic Lateral Sclerosis

Science · 1996

746

cited

Human α-synuclein-harboring familial Parkinson's disease-linked Ala-53 → Thr mutation causes neurodegenerative disease with α-synuclein aggregation in transgenic mice

Proceedings of the National Academy of Sciences of the United States of America · 2002

738

cited

Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity.

Proceedings of the National Academy of Sciences of the United States of America · 1994

632

cited

Age-Dependent Emergence and Progression of a Tauopathy in Transgenic Mice Overexpressing the Shortest Human Tau Isoform

Neuron · 1999

589

cited

Parkinson's Disease α-Synuclein Transgenic Mice Develop Neuronal Mitochondrial Degeneration and Cell Death

Journal of Neuroscience · 2006

563

cited

Aggregation promoting C-terminal truncation of alpha-synuclein is a normal cellular process and is enhanced by the familial Parkinson's disease-linked mutations.

Proceedings of the National Academy of Sciences of the United States of America · 2005

468

cited

Lysine 63-linked ubiquitination promotes the formation and autophagic clearance of protein inclusions associated with neurodegenerative diseases.

Human Molecular Genetics · 2008

461

cited

Neurofilaments are obligate heteropolymers in vivo

Journal of Cell Biology · 1993

408

cited

A mutant neurofilament subunit causes massive, selective motor neuron death: Implications for the pathogenesis of human motor neuron disease

Neuron · 1994

390

cited

Assessment of normal and mutant human presenilin function in Caenorhabditis elegans.

Proceedings of the National Academy of Sciences of the United States of America · 1996

390

cited

Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice.

Proceedings of the National Academy of Sciences of the United States of America · 2002

366

cited

Mutations associated with amyotrophic lateral sclerosis convert superoxide dismutase from an antiapoptotic gene to a proapoptotic gene: studies in yeast and neural cells.

Proceedings of the National Academy of Sciences of the United States of America · 1995

355

cited

Endoplasmic Reticulum Stress Is Important for the Manifestations of α-Synucleinopathy In Vivo

Journal of Neuroscience · 2012

334

cited

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