Sotabase

Career

· Columbia University

Publications (249)

PPARγ signaling and metabolism: the good, the bad and the future
Nature Medicine · 2013
1,831
cited
Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells
Nature · 2011
1,555
cited
AMPK and PPARδ Agonists Are Exercise Mimetics
Cell · 2008
1,119
cited
Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor.
Proceedings of the National Academy of Sciences of the United States of America · 2006
1,090
cited
Anatomical Profiling of Nuclear Receptor Expression Reveals a Hierarchical Transcriptional Network
Cell · 2006
1,006
cited
Vitamin D Receptor-Mediated Stromal Reprogramming Suppresses Pancreatitis and Enhances Pancreatic Cancer Therapy
Cell · 2014
993
cited
Regulation of Circadian Behavior and Metabolism by Rev-erbα and Rev-erbβ
Nature · 2012
953
cited
Nuclear Receptor Expression Links the Circadian Clock to Metabolism
Cell · 2006
950
cited
Humanized xenobiotic response in mice expressing nuclear receptor SXR
Nature · 2000
686
cited
A histone deacetylase corepressor complex regulates the Notch signal transduction pathway.
Genes & Development · 1998
658
cited
Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance
Nature Medicine · 2015
655
cited
A Vitamin D Receptor/SMAD Genomic Circuit Gates Hepatic Fibrotic Response
Cell · 2013
571
cited
Class IIa Histone Deacetylases Are Hormone-Activated Regulators of FOXO and Mammalian Glucose Homeostasis
Cell · 2011
565
cited
Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8+ T cells in tumors.
Immunity · 2021
563
cited
Cryptochromes mediate rhythmic repression of the glucocorticoid receptor
Nature · 2011
559
cited
Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity
Nature · 2017
500
cited
Global chemical effects of the microbiome include new bile-acid conjugations
Nature · 2020
477
cited
Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression.
Genes & Development · 2000
433
cited
Genome-wide orchestration of cardiac functions by the orphan nuclear receptors ERRalpha and gamma.
Cell Metabolism · 2007
420
cited
FXR Regulates Intestinal Cancer Stem Cell Proliferation
Cell · 2019
373
cited
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Michael Downes | Researcher Profile | Sotabase | Sotabase