· Senior Member Of Technical Staff, The Aerospace Corporation2022–
· Former Member, University of California, Berkeley
Publications (11)
Synthesis of High-Quality Antisense Drugs. Addition of Acrylonitrile to Phosphorothioate Oligonucleotides: Adduct Characterization and Avoidance
2003
71
cited
Synthesis of Antisense Oligonucleotides: Replacement of 3H-1,2-Benzodithiol-3-one 1,1-Dioxide (Beaucage Reagent) with Phenylacetyl Disulfide (PADS) As Efficient Sulfurization Reagent: From Bench to Bulk Manufacture of Active Pharmaceutical Ingredient
2000
42
cited
UnyLinker: An Efficient and Scaleable Synthesis of Oligonucleotides Utilizing a Universal Linker Molecule: A Novel Approach To Enhance the Purity of Drugs
2008
41
cited
Formation of 4,4'-dimethoxytrityl-C-phosphonate oligonucleotides.
2004
29
cited
Synthesis of antisense oligonucleotides. using environmentally friendly and safe deprotection procedures
1999
9
cited
Efficient Synthesis of Antisense Phosphorothioate Oligonucleotides: Evaluation of Dichloroacetic Acid at Higher Concentration to Reduce Cycle Time
2003
6
cited
Overcoming backpressure problems during solid-phase synthesis of oligonucleotides
2004
4
cited
Procedes de purification d'oligonucleotides
2002
Synthese d'oligonucleotides au moyen de solvants alternatifs