Sotabase

Career

· Research Associate, The University of Manchester2025–
· Research Fellow, University of Nottingham2024–2025
· Postdoctoral Researcher, The University of Manchester2022–2023
· Postdoctoral Researcher, Wroclaw University of Science and Technology2021–2022
· Assistant Professor, MGDAV College, INDIA2019–2021
· Doctor of Philosophy - PhD, Supramolecular Organic Chemistry, Guru Nanak Dev University, Amritsar2012–2018

Publications (63)

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
Autophagy · 2021
3,704
cited
Thioredoxin interacting protein (TXNIP) induces inflammation through chromatin modification in retinal capillary endothelial cells under diabetic conditions
Journal of Cellular Physiology · 2009
240
cited
TXNIP Links Innate Host Defense Mechanisms to Oxidative Stress and Inflammation in Retinal Muller Glia under Chronic Hyperglycemia: Implications for Diabetic Retinopathy
International Journal of Experimental Diabetes Research · 2012
204
cited
Inhibition of TXNIP expression in vivo blocks early pathologies of diabetic retinopathy
Cell Death and Disease · 2010
135
cited
Thioredoxin Interacting Protein (TXNIP) and Pathogenesis of Diabetic Retinopathy.
Journal of Clinical & Experimental Ophthalmology · 2013
117
cited
Critical role of TXNIP in oxidative stress, DNA damage and retinal pericyte apoptosis under high glucose: implications for diabetic retinopathy.
Experimental Cell Research · 2013
115
cited
TXNIP regulates mitophagy in retinal Müller cells under high-glucose conditions: implications for diabetic retinopathy
Cell Death and Disease · 2017
109
cited
RAGE–TXNIP axis is required for S100B-promoted Schwann cell migration, fibronectin expression and cytokine secretion
Journal of Cell Science · 2010
92
cited
An analysis of high glucose and glucosamine-induced gene expression and oxidative stress in renal mesangial cells
Archives of Physiology and Biochemistry · 2006
83
cited
Auranofin Mediates Mitochondrial Dysregulation and Inflammatory Cell Death in Human Retinal Pigment Epithelial Cells: Implications of Retinal Neurodegenerative Diseases
Frontiers in Neuroscience · 2019
81
cited
Metabolic Dysregulation and Neurovascular Dysfunction in Diabetic Retinopathy
Antioxidants · 2020
73
cited
Hexosamine-induced fibronectin protein synthesis in mesangial cells is associated with increases in cAMP responsive element binding (CREB) phosphorylation and nuclear CREB: the involvement of protein kinases A and C.
Diabetes · 2001
67
cited
TXNIP mediates high glucose-induced mitophagic flux and lysosome enlargement in human retinal pigment epithelial cells
Biology Open · 2019
52
cited
The Role of Txnip in Mitophagy Dysregulation and Inflammasome Activation in Diabetic Retinopathy: A New Perspective
JOJ Ophthalmology · 2017
50
cited
Mitophagy, Ferritinophagy and Ferroptosis in Retinal Pigment Epithelial Cells Under High Glucose Conditions: Implications for Diabetic Retinopathy and Age-Related Retinal Diseases
JOJ Ophthalmology · 2021
41
cited
Epigenetic Modifications and Potential New Treatment Targets in Diabetic Retinopathy
Journal of Ophthalmology · 2014
40
cited
Hexosamine induction of oxidative stress, hypertrophy and laminin expression in renal mesangial cells: effect of the anti‐oxidant α‐lipoic acid
Cell Biochemistry and Function · 2007
40
cited
Hexosamines and TGF-beta1 use similar signaling pathways to mediate matrix protein synthesis in mesangial cells.
AJP - Renal Physiology · 2004
39
cited
Hexosamine regulation of glucose-mediated laminin synthesis in mesangial cells involves protein kinases A and C.
AJP - Renal Physiology · 2000
35
cited
Proteomic Identification of 14-3-3ζ as an Adapter for IGF-1 and Akt/GSK-3β Signaling and Survival of Renal Mesangial Cells
International Journal on Biological Sciences · 2006
35
cited
Sotabase
Lalit Singh | Researcher Profile | Sotabase | Sotabase