Sotabase

Career

· Associate Professor, MIT Media Lab2022–
· Co-Founder, SecureDNA Foundation (Current)2022–
· Assistant Professor, MIT Media Lab2016–2023
· Wyss Technology Development Fellow, Wyss Institute for Biologically Inspired Engineering, Harvard University2011–2016
· Postdoctoral Fellow, Howard Hughes Medical Institute2010–2011
· Ph.D., Biochemistry, Harvard University2004–2010
· Ph.D Candidate, Harvard University2004–2010
· B.S., Chemistry, Biology, Harvey Mudd College2000–2004

Publications (223)

RNA-Guided Human Genome Engineering via Cas9
Science · 2013
8,879
cited
CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering
Nature Biotechnology · 2013
1,777
cited
Cas9 as a versatile tool for engineering biology
Nature Methods · 2013
1,222
cited
Heritable genome editing in C. elegans via a CRISPR-Cas9 system
Nature Methods · 2013
917
cited
Concerning RNA-guided gene drives for the alteration of wild populations
bioRxiv · 2014
745
cited
Orthogonal Cas9 Proteins for RNA-Guided Gene Regulation and Editing
Nature Methods · 2013
666
cited
A System for the Continuous Directed Evolution of Biomolecules
Nature · 2011
619
cited
Low-N protein engineering with data-efficient deep learning
Nature Methods · 2020
391
cited
Genome-scale engineering for systems and synthetic biology
Molecular Systems Biology · 2013
327
cited
The WMDP Benchmark: Measuring and Reducing Malicious Use With Unlearning
International Conference on Machine Learning · 2024
327
cited
Safeguarding CRISPR-Cas9 gene drives in yeast
Nature Biotechnology · 2015
304
cited
Regulating gene drives
Science · 2014
303
cited
Safeguarding gene drive experiments in the laboratory
Science · 2015
257
cited
Daisy-chain gene drives for the alteration of local populations
Proceedings of the National Academy of Sciences of the United States of America · 2016
209
cited
Conservation demands safe gene drive
PLoS Biology · 2017
181
cited
Current CRISPR gene drive systems are likely to be highly invasive in wild populations
bioRxiv · 2017
150
cited
Bidirectional contact tracing could dramatically improve COVID-19 control
Nature Communications · 2021
111
cited
Experimental interrogation of the path dependence and stochasticity of protein evolution using phage-assisted continuous evolution
Proceedings of the National Academy of Sciences of the United States of America · 2013
97
cited
Inhibition of Bacterial Conjugation by Phage M13 and Its Protein g3p: Quantitative Analysis and Model
PLoS ONE · 2011
88
cited
Editing nature: Local roots of global governance
Science · 2018
78
cited
Sotabase
Kevin Esvelt | Researcher Profile | Sotabase | Sotabase