Sotabase

Career

· Research Visitor, University of Pennsylvania2025–
· Visiting Graduate Student, Simons Institute for the Theory of Computing, UC Berkeley2024–
· PhD Student, Columbia University2023–
· Undergraduate Degree, UC San Diego

Publications (56)

Hepatocyte Nuclear Factor 1α Plays a Critical Role in PCSK9 Gene Transcription and Regulation by the Natural Hypocholesterolemic Compound Berberine*
Journal of Biological Chemistry · 2009
317
cited
Fatty Acid Oxidation Mediated by Acyl-CoA Synthetase Long Chain 3 Is Required for Mutant KRAS Lung Tumorigenesis.
Cell Reports · 2016
272
cited
Strong induction of PCSK9 gene expression through HNF1α and SREBP2: mechanism for the resistance to LDL-cholesterol lowering effect of statins in dyslipidemic hamsters
Journal of Lipid Research · 2010
245
cited
Magnetic resonance imaging radiomics predicts preoperative axillary lymph node metastasis to support surgical decisions and is associated with tumor microenvironment in invasive breast cancer: A machine learning, multicenter study
EBioMedicine · 2021
217
cited
Inhibition of PCSK9 Transcription by Berberine Involves Down-regulation of Hepatic HNF1α Protein Expression through the Ubiquitin-Proteasome Degradation Pathway*
Journal of Biological Chemistry · 2014
133
cited
Suppressor of Cytokine Signaling-3 (SOCS-3) Induces Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) Expression in Hepatic HepG2 Cell Line*
Journal of Biological Chemistry · 2015
96
cited
Identification of two novel regions of human IL-6 responsible for receptor binding and signal transduction.
Journal of Immunology · 1994
93
cited
Reduction of circulating PCSK9 and LDL-C levels by liver-specific knockdown of HNF1α in normolipidemic mice[S]
Journal of Lipid Research · 2015
57
cited
CETP inhibitors downregulate hepatic LDL receptor and PCSK9 expression in vitro and in vivo through a SREBP2 dependent mechanism.
Atherosclerosis · 2014
54
cited
FXR activation by obeticholic acid or nonsteroidal agonists induces a human-like lipoprotein cholesterol change in mice with humanized chimeric liver[S]
Journal of Lipid Research · 2018
49
cited
Arachidonic acid downregulates acyl-CoA synthetase 4 expression by promoting its ubiquitination and proteasomal degradation
Journal of Lipid Research · 2014
47
cited
Janus kinase activation by cytokine oncostatin M decreases PCSK9 expression in liver cells[S]
Journal of Lipid Research · 2011
47
cited
High-fructose diet downregulates long-chain acyl-CoA synthetase 3 expression in liver of hamsters via impairing LXR/RXR signaling pathway[S]
Journal of Lipid Research · 2013
46
cited
The novel function of HINFP as a co-activator in sterol-regulated transcription of PCSK9 in HepG2 cells.
Biochemical Journal · 2012
45
cited
Long Chain Acyl-CoA Synthetase-3 Is a Molecular Target for Peroxisome Proliferator-activated Receptor δ in HepG2 Hepatoma Cells*
Journal of Biological Chemistry · 2010
40
cited
Suppression of Idol expression is an additional mechanism underlying statin-induced up-regulation of hepatic LDL receptor expression.
International Journal of Molecular Medicine · 2010
40
cited
Liver-specific knockdown of long-chain acyl-CoA synthetase 4 reveals its key role in VLDL-TG metabolism and phospholipid synthesis in mice fed a high-fat diet.
American Journal of Physiology. Endocrinology and Metabolism · 2019
37
cited
SREBP2 Activation Induces Hepatic Long-chain Acyl-CoA Synthetase 1 (ACSL1) Expression in Vivo and in Vitro through a Sterol Regulatory Element (SRE) Motif of the ACSL1 C-promoter*
Journal of Biological Chemistry · 2016
36
cited
Delineation of molecular pathways that regulate hepatic PCSK9 and LDL receptor expression during fasting in normolipidemic hamsters.
Atherosclerosis · 2012
34
cited
The Critical Role of mRNA Destabilizing Protein Heterogeneous Nuclear Ribonucleoprotein D in 3′ Untranslated Region–Mediated Decay of Low-Density Lipoprotein Receptor mRNA in Liver Tissue
Arteriosclerosis, Thrombosis and Vascular Biology · 2014
34
cited
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