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Career

· Software Engineer, Rippling2022–
· Degree, UC Berkeley2009–2010

Publications (22)

Immunomodulatory oligonucleotides containing a cytosine-phosphate-2'-deoxy-7-deazaguanosine motif as potent toll-like receptor 9 agonists.
Proceedings of the National Academy of Sciences of the United States of America · 2005
92
cited
A Toll-like receptor 7, 8, and 9 antagonist inhibits Th1 and Th17 responses and inflammasome activation in a model of IL-23-induced psoriasis.
Journal of Investigative Dermatology · 2013
85
cited
Conjugation of ligands at the 5'-end of CpG DNA affects immunostimulatory activity.
Bioconjugate chemistry · 2002
84
cited
Stabilized immune modulatory RNA compounds as agonists of Toll-like receptors 7 and 8
Proceedings of the National Academy of Sciences of the United States of America · 2007
76
cited
'Immunomers'--novel 3'-3'-linked CpG oligodeoxyribonucleotides as potent immunomodulatory agents.
Nucleic Acids Research · 2002
75
cited
A novel antagonist of Toll-like receptors 7, 8 and 9 suppresses lupus disease-associated parameters in NZBW/F1 mice
Autoimmunity · 2013
63
cited
Divergent synthetic nucleotide motif recognition pattern: design and development of potent immunomodulatory oligodeoxyribonucleotide agents with distinct cytokine induction profiles.
Nucleic Acids Research · 2003
61
cited
A dinucleotide motif in oligonucleotides shows potent immunomodulatory activity and overrides species-specific recognition observed with CpG motif
Proceedings of the National Academy of Sciences of the United States of America · 2003
59
cited
Oligodeoxyribonucleotide-based antagonists for Toll-like receptors 7 and 9.
Journal of Medicinal Chemistry · 2009
43
cited
Antitumor Activity and Immune Response Induction of a Dual Agonist of Toll-Like Receptors 7 and 8
Molecular Cancer Therapeutics · 2010
39
cited
Oral administration of second-generation immunomodulatory oligonucleotides induces mucosal Th1 immune responses and adjuvant activity.
Vaccine · 2005
32
cited
CpG penta- and hexadeoxyribonucleotides as potent immunomodulatory agents.
Biochemical and Biophysical Research Communications - BBRC · 2003
31
cited
Design, synthesis, and immunostimulatory properties of CpG DNAs containing alkyl-linker substitutions: role of nucleosides in the flanking sequences.
Journal of Medicinal Chemistry · 2002
27
cited
Agonists of Toll-like receptor 9 containing synthetic dinucleotide motifs.
Journal of Medicinal Chemistry · 2007
26
cited
Novel oligonucleotides containing two 3'-ends complementary to target mRNA show optimal gene-silencing activity.
Journal of Medicinal Chemistry · 2011
18
cited
Modulation of ovalbumin-induced Th2 responses by second-generation immunomodulatory oligonucleotides in mice.
International Immunopharmacology · 2004
16
cited
Synthesis and immunological activities of novel agonists of toll-like receptor 9.
Cellular Immunology · 2010
15
cited
3D object detection from roadside data using laser scanners
Electronic imaging · 2011
12
cited
IMO-8400, a novel TLR7, TLR8 and TLR9 antagonist, inhibits disease development in mouse models of psoriasis (119.8)
Journal of Immunology · 2012
8
cited
Design of synthetic oligoribonucleotide-based agonists of Toll-like receptor 3 and their immune response profiles in vitro and in vivo.
Organic and biomolecular chemistry · 2013
6
cited
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