Ian Sweet | Researcher Profile | Sotabase

Career

· CEO, EnTox Sciences, Inc. (Current)2013–

· Associate Professor, Department Of Medicine, University of Washington (Current)1999–

· Post-Doctoral Training, Biochemistry, Biophysics and Molecular Biology, University of Pennsylvania School of Medicine1993–1996

· Doctor of Philosophy - PhD, Bioengineering, University of Washington1986–1993

Publications (102)

Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1alpha in Huntington's disease neurodegeneration.

Cell Metabolism · 2006

601

cited

Biochemical adaptations of the retina and retinal pigment epithelium support a metabolic ecosystem in the vertebrate eye

bioRxiv · 2017

292

cited

Activation of NF-&kgr;B by Palmitate in Endothelial Cells: A Key Role for NADPH Oxidase-Derived Superoxide in Response to TLR4 Activation

Arteriosclerosis, Thrombosis and Vascular Biology · 2009

226

cited

NADPH Oxidase-derived Reactive Oxygen Species Increases Expression of Monocyte Chemotactic Factor Genes in Cultured Adipocytes*

Journal of Biological Chemistry · 2012

184

cited

Mutants of glucokinase cause hypoglycaemia- and hyperglycaemia syndromes and their analysis illuminates fundamental quantitative concepts of glucose homeostasis

Diabetologia · 1999

161

cited

Effect of the two-layer (University of Wisconsin solution–perfluorochemical plus O2) method of pancreas preservation on human islet isolation, as assessed by the Edmonton Isolation Protocol1

Transplantation · 2002

152

cited

The Fractalkine/CX3CR1 System Regulates β Cell Function and Insulin Secretion

Cell · 2013

138

cited

Flow of energy in the outer retina in darkness and in light

Proceedings of the National Academy of Sciences of the United States of America · 2010

120

cited

This Work Is Licensed under a Creative Commons Attribution 4.0 International License Neural Stem Cells in the Adult Subventricular Zone Oxidize Fatty Acids to Produce Energy and Support Neurogenic Activity Significance Statement

120

cited

Development and characterization of a novel rat model of type 2 diabetes mellitus: the UC Davis type 2 diabetes mellitus UCD-T2DM rat.

American Journal of Physiology. Regulatory Integrative and Comparative Physiology · 2008

115

cited

Continuous Measurement of Oxygen Consumption by Pancreatic Islets

Diabetes Technology & Therapeutics · 2002

cited

M2 Macrophage Polarization Mediates Anti-inflammatory Effects of Endothelial Nitric Oxide Signaling

Diabetes · 2015

cited

Regulation of ATP/ADP in pancreatic islets.

Diabetes · 2004

cited

Systematic screening of potential β-cell imaging agents

2004

cited

Phototransduction Influences Metabolic Flux and Nucleotide Metabolism in Mouse Retina*

Journal of Biological Chemistry · 2015

cited

Glucose‐Stimulated Increment in Oxygen Consumption Rate as a Standardized Test of Human Islet Quality

American Journal of Transplantation · 2007

cited

Insulin secretion in the conscious mouse is biphasic and pulsatile.

American Journal of Physiology. Endocrinology and Metabolism · 2006

cited

Inhibition of Mitochondrial Pyruvate Transport by Zaprinast Causes Massive Accumulation of Aspartate at the Expense of Glutamate in the Retina*

Journal of Biological Chemistry · 2013

cited

Rapid Reduction and Return of Surface Insulin Receptors After Exposure to Brief Pulses of Insulin in Perifused Rat Hepatocytes

Diabetes · 1988

cited

Roles of Glucose in Photoreceptor Survival*

Journal of Biological Chemistry · 2011

cited

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