Sotabase

Career

· Ph.D. in Electrical Engineering, MIT1973–
· Senior Research Scientist, MIT Computer Science and Artificial Intelligence Laboratory (CSAIL)1973–
· MS in Electrical Engineering and Computer Science, MIT1969–
· BS in Electrical Engineering, Swarthmore College1966–

Publications (174)

Early role of vascular dysregulation on late-onset Alzheimer's disease based on multifactorial data-driven analysis
Nature Communications · 2016
1,004
cited
Four distinct trajectories of tau deposition identified in Alzheimer’s disease
Nature Medicine · 2021
564
cited
Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE
Nature Communications · 2015
320
cited
Basal forebrain degeneration precedes and predicts the cortical spread of Alzheimer’s pathology
Nature Communications · 2016
284
cited
Functional brain architecture is associated with the rate of tau accumulation in Alzheimer’s disease
Nature Communications · 2020
273
cited
NIRA: A New Inter-Domain Routing Architecture
IEEE/ACM Transactions on Networking · 2007
243
cited
Novel late-onset Alzheimer disease loci variants associate with brain gene expression
Neurology · 2012
163
cited
Challenges and Opportunities with Causal Discovery Algorithms: Application to Alzheimer’s Pathophysiology
Scientific Reports · 2020
144
cited
Neuronal exosomes reveal Alzheimer's disease biomarkers in Down syndrome
Alzheimer's & Dementia · 2017
118
cited
Hexanucleotide repeat expansions in C9ORF72 in the spectrum of motor neuron diseases
Neurology · 2012
117
cited
Alzheimer disease pathology in cognitively healthy elderly: A genome-wide study
Neurobiology of Aging · 2011
110
cited
Non-coding variability at the APOE locus contributes to the Alzheimer’s risk
Nature Communications · 2019
106
cited
Temporal order of clinical and biomarker changes in familial frontotemporal dementia
Nature Medicine · 2022
105
cited
Brain multiplexes reveal morphological connectional biomarkers fingerprinting late brain dementia states
Scientific Reports · 2018
100
cited
NIH electronic cigarette workshop: developing a research agenda.
Nicotine & Tobacco Research · 2015
100
cited
Amyloid-associated increases in soluble tau relate to tau aggregation rates and cognitive decline in early Alzheimer’s disease
Nature Communications · 2022
91
cited
Robust Identification of Alzheimer’s Disease subtypes based on cortical atrophy patterns
Scientific Reports · 2017
84
cited
Accelerated functional brain aging in pre-clinical familial Alzheimer’s disease
Nature Communications · 2021
83
cited
The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory
Nature Communications · 2019
79
cited
#COVIDisAirborne: AI-enabled multiscale computational microscopy of delta SARS-CoV-2 in a respiratory aerosol
bioRxiv · 2021
77
cited
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