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· Microsoft Research

Publications (111)

Cell-intrinsic lysosomal lipolysis is essential for macrophage alternative activation
Nature Immunology · 2014
772
cited
CD45 Phosphatase Inhibits STAT3 Transcription Factor Activity in Myeloid Cells and Promotes Tumor-Associated Macrophage Differentiation.
Immunity · 2016
347
cited
The regulatory enzymes and protein substrates for the lysine β-hydroxybutyrylation pathway
Science Advances · 2021
170
cited
Activation of the signal transducers and activators of the transcription 3 pathway in alveolar epithelial cells induces inflammation and adenocarcinomas in mouse lung.
Cancer Research · 2007
153
cited
Matrix metalloproteinase 12 overexpression in lung epithelial cells plays a key role in emphysema to lung bronchioalveolar adenocarcinoma transition.
Cancer Research · 2009
97
cited
Signal transducer and activator of transcription 3 (Stat3C) promotes myeloid-derived suppressor cell expansion and immune suppression during lung tumorigenesis.
American Journal of Pathology · 2011
96
cited
Stat3 downstream genes serve as biomarkers in human lung carcinomas and chronic obstructive pulmonary disease.
Lung Cancer · 2009
93
cited
Lysosomal acid lipase deficiency causes respiratory inflammation and destruction in the lung.
American Journal of Physiology - Lung cellular and Molecular Physiology · 2004
92
cited
Inhibition of PPARγ in myeloid-lineage cells induces systemic inflammation, immunosuppression, and tumorigenesis.
Blood · 2012
91
cited
A scalable architecture for ordered parallelism
Micro · 2015
88
cited
Hepatocyte nuclear factor‐3β limits cellular diversity in the developing respiratory epithelium and alters lung morphogenesis in vivo
Developmental Dynamics · 1997
80
cited
Abstract 794: Matrix metalloproteinase 12 overexpression in myeloid lineage cells plays a key role in modulating myelopoiesis, immune suppression and lung tumorigenesis
2011
79
cited
Macrophage-specific expression of human lysosomal acid lipase corrects inflammation and pathogenic phenotypes in lal-/- mice.
American Journal of Pathology · 2006
75
cited
Transcriptional Stimulation of the Surfactant Protein B Gene by STAT3 in Respiratory Epithelial Cells*
Journal of Biological Chemistry · 2002
70
cited
How not to Structure Your Database-Backed Web Applications: A Study of Performance Bugs in the Wild
International Conference on Software Engineering · 2018
68
cited
Neutral lipids and peroxisome proliferator-activated receptor-{gamma} control pulmonary gene expression and inflammation-triggered pathogenesis in lysosomal acid lipase knockout mice.
American Journal of Pathology · 2005
65
cited
Leveraging Lock Contention to Improve OLTP Application Performance
Proceedings of the VLDB Endowment · 2016
64
cited
Activation of mTOR Pathway in Myeloid-derived Suppressor Cells Stimulates Cancer Cell Proliferation and Metastasis in lal−/− Mice
Oncogene · 2014
62
cited
Retinoic Acid Stimulation of the Human Surfactant Protein B Promoter Is Thyroid Transcription Factor 1 Site-dependent*
Journal of Biological Chemistry · 2000
59
cited
Lysosome-mediated degradation of a distinct pool of lipid droplets during hepatic stellate cell activation
Journal of Biological Chemistry · 2017
55
cited
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