Sotabase

Career

· Researcher, Illinois Security Lab2024–
· Researcher, University of Illinois at Urbana-Champaign2012–2016

Publications (52)

Simulation of the clinical and pathological manifestations of Coronavirus Disease 2019 (COVID-19) in golden Syrian hamster model: implications for disease pathogenesis and transmissibility
Clinical Infectious Diseases · 2020
996
cited
SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target
Nature Communications · 2019
275
cited
Clofazimine broadly inhibits coronaviruses including SARS-CoV-2
Nature · 2021
177
cited
Differential cell line susceptibility to the emerging Zika virus: implications for disease pathogenesis, non-vector-borne human transmission and animal reservoirs
Emerging Microbes and Infections · 2016
161
cited
Pathogenicity, transmissibility, and fitness of SARS-CoV-2 Omicron in Syrian hamsters
Science · 2022
160
cited
A novel peptide with potent and broad-spectrum antiviral activities against multiple respiratory viruses
Scientific Reports · 2016
159
cited
Emerging SARS-CoV-2 variants expand species tropism to murines
EBioMedicine · 2021
155
cited
Oral SARS-CoV-2 Inoculation Establishes Subclinical Respiratory Infection with Virus Shedding in Golden Syrian Hamsters
Cell Reports Medicine · 2020
126
cited
Leptin mediates the pathogenesis of severe 2009 pandemic influenza A(H1N1) infection associated with cytokine dysregulation in mice with diet-induced obesity.
Journal of Infectious Diseases · 2013
116
cited
Structure‐based discovery of clinically approved drugs as Zika virus NS2B‐NS3 protease inhibitors that potently inhibit Zika virus infection in vitro and in vivo
Antiviral Research · 2017
111
cited
Novel antiviral activity and mechanism of bromocriptine as a Zika virus NS2B‐NS3 protease inhibitor
Antiviral Research · 2017
109
cited
Coinfection by Severe Acute Respiratory Syndrome Coronavirus 2 and Influenza A(H1N1)pdm09 Virus Enhances the Severity of Pneumonia in Golden Syrian Hamsters
Clinical Infectious Diseases · 2020
103
cited
SARS-CoV-2 infects and damages the mature and immature olfactory sensory neurons of hamsters
Clinical Infectious Diseases · 2020
101
cited
Robust SARS-CoV-2 infection in nasal turbinates after treatment with systemic neutralizing antibodies
Cell Host and Microbe · 2021
88
cited
Zika Virus Infection in Dexamethasone-immunosuppressed Mice Demonstrating Disseminated Infection with Multi-organ Involvement Including Orchitis Effectively Treated by Recombinant Type I Interferons
EBioMedicine · 2016
82
cited
D225G mutation in hemagglutinin of pandemic influenza H1N1 (2009) virus enhances virulence in mice
Experimental biology and medicine · 2010
81
cited
Wild Type and Mutant 2009 Pandemic Influenza A (H1N1) Viruses Cause More Severe Disease and Higher Mortality in Pregnant BALB/c Mice
PLoS ONE · 2010
80
cited
CL-385319 inhibits H5N1 avian influenza A virus infection by blocking viral entry.
European Journal of Pharmacology · 2011
71
cited
Coronaviruses exploit a host cysteine-aspartic protease for replication
Nature · 2022
64
cited
Cross-linking peptide and repurposed drugs inhibit both entry pathways of SARS-CoV-2
Nature Communications · 2020
58
cited
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Chris Chan | Researcher Profile | Sotabase | Sotabase