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Career

· Researcher, Massachusetts Institute of Technology (MIT) Interactive Robotics Group2024–

Publications (135)

Structure-Guided Blockade of CSF1R Kinase in Tenosynovial Giant-Cell Tumor.
New England Journal of Medicine · 2015
457
cited
Malignant Peripheral Nerve Sheath Tumor.
Surgical Oncology Clinics of North America · 2016
167
cited
Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma
Nature Communications · 2022
147
cited
Tumor-targeting Salmonella typhimurium A1-R in combination with doxorubicin eradicate soft tissue sarcoma in a patient-derived orthotopic xenograft (PDOX) model
OncoTarget · 2016
123
cited
Effective molecular targeting of CDK4/6 and IGF-1R in a rare FUS-ERG fusion CDKN2A-deletion doxorubicin-resistant Ewing's sarcoma patient-derived orthotopic xenograft (PDOX) nude-mouse model
OncoTarget · 2016
102
cited
High efficacy of tumor-targeting Salmonella typhimurium A1-R on a doxorubicin- and dactolisib-resistant follicular dendritic-cell sarcoma in a patient-derived orthotopic xenograft PDOX nude mouse model
OncoTarget · 2016
99
cited
Patient-reported Symptoms of Tenosynovial Giant Cell Tumors
Clinical Therapeutics · 2016
95
cited
Nucleoside salvage pathway kinases regulate hematopoiesis by linking nucleotide metabolism with replication stress
Journal of Experimental Medicine · 2012
93
cited
Tumor-targeting Salmonella typhimurium A1-R combined with temozolomide regresses malignant melanoma with a BRAF-V600E mutation in a patient-derived orthotopic xenograft (PDOX) model
OncoTarget · 2016
85
cited
In vivo models of prostate cancer metastasis to bone.
Journal of Urology · 2005
81
cited
Recombinant methioninase effectively targets a Ewing's sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model
OncoTarget · 2017
81
cited
A Phase II Trial of 5-Day Neoadjuvant Radiotherapy for Patients with High-Risk Primary Soft Tissue Sarcoma
Clinical Cancer Research · 2020
76
cited
A Pilot Trial of the Combination of Transgenic NY-ESO-1–reactive Adoptive Cellular Therapy with Dendritic Cell Vaccination with or without Ipilimumab
Clinical Cancer Research · 2018
76
cited
Tumor-targeting Salmonella typhimurium A1-R combined with recombinant methioninase and cisplatinum eradicates an osteosarcoma cisplatinum-resistant lung metastasis in a patient-derived orthotopic xenograft (PDOX) mouse model: decoy, trap and kill chemotherapy moves toward the clinic
Cell Cycle · 2018
73
cited
Recombinant methioninase in combination with doxorubicin (DOX) overcomes first-line DOX resistance in a patient-derived orthotopic xenograft nude-mouse model of undifferentiated spindle-cell sarcoma.
Cancer Letters · 2018
71
cited
Oral Recombinant Methioninase Combined with Caffeine and Doxorubicin Induced Regression of a Doxorubicin-resistant Synovial Sarcoma in a PDOX Mouse Model
Anticancer Research · 2018
67
cited
Overall survival and histology‐specific subgroup analyses from a phase 3, randomized controlled study of trabectedin or dacarbazine in patients with advanced liposarcoma or leiomyosarcoma
Cancer · 2019
63
cited
Biologics: Targets and Therapy Dovepress Giant-cell Tumor of Bone: Treatment Options and Role of Denosumab
60
cited
Infiltration of CD8 T Cells and Expression of PD-1 and PD-L1 in Synovial Sarcoma
Cancer immunology research · 2016
59
cited
Intra-arterial administration of tumor-targeting Salmonella typhimurium A1-R regresses a cisplatin-resistant relapsed osteosarcoma in a patient-derived orthotopic xenograft (PDOX) mouse model
Cell Cycle · 2017
58
cited
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