Sotabase

Career

· Senior Data Engineer, Rebuy Engine2023–
· Data Engineer, Demographic Frame Program, U.S. Census Bureau2023–
· Data Science Fellow, University of California, Berkeley2022–
· Operations and Data Specialist, Center for Care Innovations2020–
· Program Coordinator, Center for Care Innovations2017–
· Associate Consultant, Triage Consulting Group2015–

Publications (44)

Cloning and sequencing of cDNA encoding human DNA topoisomerase II and localization of the gene to chromosome region 17q21-22.
Proceedings of the National Academy of Sciences of the United States of America · 1988
368
cited
Substituted 2,5'-Bi-1H-benzimidazoles: topoisomerase I inhibition and cytotoxicity.
Journal of Medicinal Chemistry · 1996
223
cited
Hydrogen Peroxide Induces Topoisomerase I-mediated DNA Damage and Cell Death*
Journal of Biological Chemistry · 2004
140
cited
Direct Evidence that Saquinavir Is Transported by Multidrug Resistance-Associated Protein (MRP1) and Canalicular Multispecific Organic Anion Transporter (MRP2)
Antimicrobial Agents and Chemotherapy · 2002
131
cited
5H-Dibenzo[c,h]1,6-naphthyridin-6-ones: novel topoisomerase I-targeting anticancer agents with potent cytotoxic activity.
Bioorganic & Medicinal Chemistry · 2003
92
cited
Characterization of ARC-111 as a novel topoisomerase I-targeting anticancer drug.
Cancer Research · 2003
91
cited
5-(2-aminoethyl)dibenzo[c,h][1,6]naphthyridin-6-ones: variation of n-alkyl substituents modulates sensitivity to efflux transporters associated with multidrug resistance.
Journal of Medicinal Chemistry · 2005
89
cited
Macrocyclic pyridyl polyoxazoles: selective RNA and DNA G-quadruplex ligands as antitumor agents.
Journal of Medicinal Chemistry · 2010
78
cited
The role of the tissue omega-6/omega-3 fatty acid ratio in regulating tumor angiogenesis
Cancer Metastasis Review · 2012
77
cited
Substituted dibenzo[c,h]cinnolines: topoisomerase I-targeting anticancer agents.
Bioorganic & Medicinal Chemistry · 2003
76
cited
11H-Isoquino[4,3-c]cinnolin-12-ones; novel anticancer agents with potent topoisomerase I-targeting activity and cytotoxicity.
Bioorganic & Medicinal Chemistry · 2004
67
cited
G-quadruplexes induce apoptosis in tumor cells.
Cancer Research · 2006
61
cited
Mutations of human topoisomerase IIα affecting multidrug resistance and sensitivity
1999
54
cited
Diaza- and triazachrysenes: potent topoisomerase-targeting agents with exceptional antitumor activity against the human tumor xenograft, MDA-MB-435.
Bioorganic & Medicinal Chemistry Letters · 2002
52
cited
Esters and amides of 2,3-dimethoxy-8,9-methylenedioxy-benzo[i]phenanthridine-12-carboxylic acid: potent cytotoxic and topoisomerase I-targeting agents.
Bioorganic & Medicinal Chemistry · 2005
47
cited
Heterocyclic bibenzimidazole derivatives as topoisomerase I inhibitors.
Bioorganic & Medicinal Chemistry Letters · 2000
46
cited
Nitro and amino substitution in the D-ring of 5-(2-dimethylaminoethyl)- 2,3-methylenedioxy-5H-dibenzo[c,h][1,6]naphthyridin-6-ones: effect on topoisomerase-I targeting activity and cytotoxicity.
Journal of Medicinal Chemistry · 2003
45
cited
2,3-Dimethoxybenzo[i]phenanthridines: topoisomerase I-targeting anticancer agents.
Bioorganic & Medicinal Chemistry · 2003
40
cited
Structure activity of topoisomerase i poisons related to hoechst 33342
1994
38
cited
Differential poisoning of topoisomerases by menogaril and nogalamycin dictated by the minor groove-binding nogalose sugar.
Biochemistry · 1997
37
cited
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Angela Liu | Researcher Profile | Sotabase | Sotabase