Sotabase

Career

· Researcher, MIT CSAIL Theory of Computation Group2024–
· Hitachi America Professor of Engineering, Massachusetts Institute of Technology (MIT)1991–2016
· Visiting Professor, Division of Applied Science, Harvard University1978–1979
· Professor, Massachusetts Institute of Technology (MIT)1969–1991
· Professor Emeritus of Computer Science, Massachusetts Institute of Technology (MIT)1969–2019
· Assistant Professor, Carnegie-Mellon University1967–1969

Publications (204)

Microwave assisted "click" chemistry for the synthesis of multiple labeled-carbohydrate oligonucleotides on solid support.
Journal of Organic Chemistry · 2006
156
cited
DNA-based carbohydrate biochips: a platform for surface glyco-engineering.
Angewandte Chemie · 2007
145
cited
Fucosylated pentaerythrityl phosphodiester oligomers (PePOs): automated synthesis of DNA-based glycoclusters and binding to Pseudomonas aeruginosa lectin (PA-IIL).
Bioconjugate chemistry · 2007
89
cited
Synthesis of mannose and galactose oligonucleotide conjugates by bi-click chemistry.
Journal of Organic Chemistry · 2009
79
cited
New strategies for cyclization and bicyclization of oligonucleotides by click chemistry assisted by microwaves.
Journal of Organic Chemistry · 2008
75
cited
Azide solid support for 3'-conjugation of oligonucleotides and their circularization by click chemistry.
Journal of Organic Chemistry · 2009
71
cited
Design of Triazole‐Tethered Glycoclusters Exhibiting Three Different Spatial Arrangements and Comparative Study of their Affinities towards PA‐IL and RCA 120 by Using a DNA‐Based Glycoarray
ChemBioChem · 2009
67
cited
Synthesis of a library of fucosylated glycoclusters and determination of their binding toward Pseudomonas aeruginosa lectin B (PA-IIL) using a DNA-based carbohydrate microarray.
Bioconjugate chemistry · 2012
50
cited
DNA-directed immobilisation of glycomimetics for glycoarrays application: comparison with covalent immobilisation, and development of an on-chip IC50 measurement assay.
Biosensors & bioelectronics · 2009
46
cited
Stereoisomers of Deoxynucleoside 5′-Triphosphates as Substrates for Template-dependent and -independent DNA Polymerases*
Journal of Biological Chemistry · 1997
43
cited
Oligonucleotide carbohydrate-centered galactosyl cluster conjugates synthesized by click and phosphoramidite chemistries.
Bioconjugate chemistry · 2010
39
cited
Fluorescence enhancement upon G-quadruplex folding: synthesis, structure, and biophysical characterization of a dansyl/cyclodextrin-tagged thrombin binding aptamer.
Bioconjugate chemistry · 2013
37
cited
Fluorescent Thrombin Binding Aptamer-Tagged Nanoparticles for an Efficient and Reversible Control of Thrombin Activity.
ACS Applied Materials and Interfaces · 2017
36
cited
Oligonucleotide sequential bis-conjugation via click-oxime and click-Huisgen procedures.
Journal of Organic Chemistry · 2010
36
cited
Structure binding relationship of galactosylated Glycoclusters toward Pseudomonas aeruginosa lectin LecA using a DNA-based carbohydrate microarray.
Bioconjugate chemistry · 2014
34
cited
Specific recognition of lectins by oligonucleotide glycoconjugates and sorting on a DNA microarray.
Chemical Communications · 2009
32
cited
Toward the Rational Design of Galactosylated Glycoclusters That Target Pseudomonas aeruginosa Lectin A (LecA): Influence of Linker Arms That Lead to Low-Nanomolar Multivalent Ligands.
Chemistry · 2016
32
cited
Mannose-centered aromatic galactoclusters inhibit the biofilm formation of Pseudomonas aeruginosa.
Organic and biomolecular chemistry · 2015
31
cited
Combinatorial and automated synthesis of phosphodiester galactosyl cluster on solid support by click chemistry assisted by microwaves.
Journal of Organic Chemistry · 2008
30
cited
Design, Synthesis and Characterization of Cyclic NU172 Analogues: A Biophysical and Biological Insight
International Journal of Molecular Sciences · 2020
30
cited
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