Sotabase

Career

· Fellowship, Orthopaedic Trauma, Stanford Health Care2015–2016
· PhD Student, Stanford University School of Medicine2005–2008
· Research, Genentech
· Genentech
· Chief Scientific Officer, GigaGen
· Grifols
· Research Management, LakePharma (now Curia)
· B.A. in Biological Sciences, Northwestern University
· Ph.D. in Cancer Biology, Stanford University School of Medicine
· Postdoctoral Researcher, Stanford University School of Medicine

Publications (121)

Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren’s syndrome
Nature Genetics · 2013
494
cited
CD4+ T Cell Tolerance to Parenchymal Self-Antigens Requires Presentation by Bone Marrow–derived Antigen-presenting Cells
Journal of Experimental Medicine · 1998
326
cited
Safety and feasibility of injection with an E1B-55 kDa gene-deleted, replication-selective adenovirus (ONYX-015) into primary carcinomas of the pancreas: a phase I trial
Gene Therapy · 2001
298
cited
Macrophage polarization and meta-inflammation.
Translational research : the journal of laboratory and clinical medicine · 2018
297
cited
Androgen ablation mitigates tolerance to a prostate/prostate cancer-restricted antigen.
Cancer Cell · 2005
296
cited
Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort
Genes and Immunity · 2011
260
cited
Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells.
Blood · 2012
249
cited
High-density genotyping of immune-related loci identifies new SLE risk variants in individuals with Asian ancestry
Nature Genetics · 2016
245
cited
Association of Genetic Variants in Complement Factor H and Factor H-Related Genes with Systemic Lupus Erythematosus Susceptibility
PLoS Genetics · 2011
212
cited
Tc17 CD8 T Cells: Functional Plasticity and Subset Diversity1
Journal of Immunology · 2009
207
cited
Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study.
American Journal of Human Genetics · 2012
178
cited
CD134 Plus CD137 Dual Costimulation Induces Eomesodermin in CD4 T Cells To Program Cytotoxic Th1 Differentiation
Journal of Immunology · 2011
161
cited
Genome‐Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture
Arthritis & Rheumatology · 2015
157
cited
Glycoprotein 96 Can Chaperone Both MHC Class I- and Class II-Restricted Epitopes for In Vivo Presentation, but Selectively Primes CD8+ T Cell Effector Function 1
Journal of Immunology · 2004
148
cited
Admixture Mapping in Lupus Identifies Multiple Functional Variants within IFIH1 Associated with Apoptosis, Inflammation, and Autoantibody Production
PLoS Genetics · 2013
118
cited
Genome-Wide Association Study of African and European Americans Implicates Multiple Shared and Ethnic Specific Loci in Sarcoidosis Susceptibility
PLoS ONE · 2012
118
cited
Fine mapping of Xq28: both MECP2 and IRAK1 contribute to risk for systemic lupus erythematosus in multiple ancestral groups
Annals of the Rheumatic Diseases · 2012
106
cited
In Vivo CD4+ T Cell Tolerance Induction Versus Priming Is Independent of the Rate and Number of Cell Divisions1
Journal of Immunology · 2000
105
cited
IL-17 inhibits CXCL9/10-mediated recruitment of CD8+ cytotoxic T cells and regulatory T cells to colorectal tumors
Journal of Immunotherapy for Cancer · 2019
104
cited
The stringency and magnitude of androgen-specific gene activation are combinatorial functions of receptor and nonreceptor binding site sequences
Molecular and Cellular Biology · 1993
96
cited
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Adam Adler | Researcher Profile | Sotabase | Sotabase