Sotabase

Career

· Interim CEO, President, Director, Link Cell Therapies2022–
· President, Cargo Therapeutics2021–2022
· Principal, Samsara BioCapital2021–
· Director of Program Biology, Revolution Medicines2014–2017
· Founder & CEO, Aurora Medical2012–2014
· Associate Director of Program Management, bluebird bio2010–2012
· AB in Molecular Biology, Princeton University2008–
· MS in Developmental Biology, Stanford University2008–
· Bluebird Bio
· Associate, Third Rock Ventures

Publications (68)

The role of the European Chemicals Bureau in promoting the regulatory use of (Q)SAR methods
SAR and QSAR in environmental research (Print) · 2007
139
cited
Mechanism of dioxygen activation in 2-oxoglutarate-dependent enzymes: a hybrid DFT study.
Chemistry · 2004
136
cited
The origin of stereoselectivity in primary amino acid catalyzed intermolecular aldol reactions.
Angewandte Chemie · 2005
112
cited
A Density Functional Study of O−O Bond Cleavage for a Biomimetic Non-Heme Iron Complex Demonstrating an FeV-Intermediate
2002
110
cited
A theoretical study of the cis-dihydroxylation mechanism in naphthalene 1,2-dioxygenase
JBIC Journal of Biological Inorganic Chemistry · 2004
90
cited
The Characterisation of (Quantitative) Structure-Activity Relationships: Preliminary Guidance
2005
87
cited
Two faces of a biomimetic non-heme HO-Fe(v)=O oxidant: olefin epoxidation versus cis-dihydroxylation.
Angewandte Chemie · 2005
84
cited
Quantum chemical studies of dioxygen activation by mononuclear non-heme iron enzymes with the 2-His-1-carboxylate facial triad.
Dalton Transactions · 2004
80
cited
4-Hydroxyphenylpyruvate dioxygenase: a hybrid density functional study of the catalytic reaction mechanism.
Biochemistry · 2004
77
cited
A density functional study on a biomimetic non-heme iron catalyst: insights into alkane hydroxylation by a formally HO-FeV=O oxidant.
Chemistry · 2005
67
cited
Predicting acute contact toxicity of pesticides in honeybees (Apis mellifera) through a k-nearest neighbor model.
Chemosphere · 2017
60
cited
Mechanism of aromatic hydroxylation by an activated FeIV=O core in tetrahydrobiopterin-dependent hydroxylases.
Chemistry · 2003
57
cited
Mechanism of dioxygen cleavage in tetrahydrobiopterin-dependent amino acid hydroxylases.
Chemistry · 2003
52
cited
EFSA's OpenFoodTox: An open source toxicological database on chemicals in food and feed and its future developments.
Environment International · 2021
51
cited
Theoretical studies of enzyme mechanisms involving high-valent iron intermediates.
Journal of Inorganic Biochemistry · 2006
43
cited
Evaluation of the applicability of existing (Q)SAR models for predicting the genotoxicity of pesticides and similarity analysis related with genotoxicity of pesticides for facilitating of grouping and read across
EFSA Supporting Publications · 2019
42
cited
Ethylene biosynthesis by 1-aminocyclopropane-1-carboxylic acid oxidase: a DFT study.
Chemistry · 2006
35
cited
Identifying isomers of C-78 by means of x-ray spectroscopy
2002
32
cited
In Silico Approaches In Carcinogenicity Hazard Assessment: Current Status and Future Needs.
Computational Toxicology · 2021
32
cited
In silico approaches in organ toxicity hazard assessment: Current status and future needs for predicting heart, kidney and lung toxicities.
Computational Toxicology · 2021
32
cited
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Abe Bassan | Researcher Profile | Sotabase | Sotabase